Homing Endonucleases and Inteins

Download or read book Homing Endonucleases and Inteins written by Marlene Belfort and published by Springer Science & Business Media. This book was released on 2008-09-22 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the first and only comprehensive description and detailed summary of the genetics, structure, function, mechanisms of action, evolution and engineering of homing endonucleases and inteins. These two unique protein superfamilies, which are tied together through their frequent fusion and coevolution, have generated considerable excitement for their fundamental, structural, and functional properties, their evolution as parasitic elements, and their widespread applications as gene targeting agents and as instruments for the generation of modified proteins and novel protein combinations.